The Quaternary Structure of Amalgam, a Drosophila Neuronal Adhesion Protein, Explains Its Dual Adhesion Properties
نویسندگان
چکیده
منابع مشابه
The quaternary structure of amalgam, a Drosophila neuronal adhesion protein, explains its dual adhesion properties.
Amalgam (Ama) is a secreted neuronal adhesion protein that contains three tandem immunoglobulin domains. It has both homophilic and heterophilic cell adhesion properties, and is required for axon guidance and fasciculation during early stages of Drosophila development. Here, we report its biophysical characterization and use small-angle x-ray scattering to determine its low-resolution structure...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2009.07.045